Muscle Metabolism and Physiology Lab

Nick Berger presents in Boston, MA. Partial Knockout of Skeletal Muscle Dynamin-Related Protein 1 Modulates Mitochondrial Quality Controls Proteins After Exercise.

Nick Berger presents in Long Beach, CA. Effects of Partial Knockout of Skeletal Muscle Dynamin-Related Protein 1 on Skeletal Muscle Characteristics in Lean and Obese Mice.

Congratulations to Masters student Grace Rosen for successfully defending her M.S. thesis entitled “Effects of mitochondrial fission inhibition of mitochondrial quality and muscle function in D2-mdx mouse model of Duchenne Muscular Dystrophy”. Grace recently accepted a position at Biocytogen at… Continue Reading →

Nick presented skeletal muscle characteristics of lean and obese Drp-1 partial knockout C57BL6 mice. Grace presented on mitochondrial structure and function and resulting effects of inhibition of mitochondrial fission in D2-mdx mice. Elizabeth presented on methods of generating a homozygous… Continue Reading →

Our paper titled “Development and characterization of a first-in-class adjustable-dose gene therapy system” was published in Gene. Remedium Bio and the Zou Lab announced the publication of preclinical data demonstrating the performance of the adjustable dose gene therapy platform –… Continue Reading →

Former MS student James Tincknell’s thesis work is accepted for publication in Applied Physiology, Nutrition, and Metabolism. James’s thesis was focused on the effects of high-intensity interval training on regulatory machinery of mitochondrial quality control in skeletal muscle of obese mice. Former… Continue Reading →

Our paper titled “Partial skeletal muscle-specific Drp1 knockout enhances insulin sensitivity in diet-induced obese mice, but not in lean mice” was published in Molecular Metabolism. demonstrate that partial loss of skeletal muscle-specific Drp1 expression is sufficient to improve whole-body glucose… Continue Reading →

A huge thank you to Nicole for her last year’s dedication to the lab and science. Good luck on your next adventures on the west coast!

Remedium Bio announces the receipt of a National Science Foundation (NSF) Phase I Small Business Innovation Research (SBIR) grant to support the development of the Prometheus™ dose-adjustable gene therapy platform technology. Dr. Zou is Co-Investigator on this funded project. Our collaboration with them… Continue Reading →

Nick Berger presents in Denver, CO. Voluntary Wheel Running Alters Mitochondrial Fission Protein DRP1 in Castration-Resistant Prostate Cancer.